The Influence of Permeability through Bacterial Porins in Whole-Cell Compound Accumulation

The lack of new drugs for Gram-negative pathogens is a global threat to modern medicine. The complexity of their cell envelope, with an additional outer membrane, hinders internal accumulation and thus, the access of molecules to their targets. Our limited understanding of the molecular basis for co...

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Bibliographic Details

Published in:	Antibiotics (Basel) Vol. 10; no. 6; p. 635
Main Authors:	Acosta-Gutiérrez, Silvia, Bodrenko, Igor, Ceccarelli, Matteo
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 26-05-2021 MDPI
Subjects:	Accumulation Antibacterial materials Antibiotics Bacteria Datasets E coli Efflux Genomics Gram-negative bacteria Gram-positive bacteria Pathogens Permeability Permeability coefficient Porins RNA polymerase
Online Access:	Get full text
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