Alterations in Cell Cycle Genes in Early Stage Lung Adenocarcinoma Identified by Expression Profiling

In normal lung epithelial cells, cellular division is an ordered, tightly regulated process involving multiple checkpoints that assess extracellular growth signals, cell size, and DNA integrity. In contrast, neoplastic lung cells develop the ability to bypass several of these checkpoints, particular...

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Bibliographic Details
Published in:	Cancer biology & therapy Vol. 2; no. 3; pp. 291 - 298
Main Authors:	Singhal, Sunil, Amin, Kunjilata, Kruklitis, Robert, DeLong, Peter, Friscia, Michael E., Litzky, Leslie A., Putt, Mary E., Kaiser, Larry R., Albelda, Steven M.
Format:	Journal Article
Language:	English
Published:	United States Taylor & Francis 01-05-2003
Subjects:	Adenocarcinoma - genetics Adenocarcinoma - metabolism Aged Binding Biology Bioscience Calcium Cancer Cell Cell Cycle - genetics Cycle Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Genes, cdc - physiology Humans Landes Lung Neoplasms - genetics Lung Neoplasms - metabolism Male Neoplasm Proteins - metabolism Neoplasm Staging Oligonucleotide Array Sequence Analysis - methods Organogenesis Proteins RNA, Messenger - metabolism Transcription, Genetic
Online Access:	Get full text
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