Downregulation of CRNN gene and genomic instability at 1q21.3 in oral squamous cell carcinoma

Objectives This study includes the direct sequencing of cornulin (CRNN) gene to elucidate the possible mechanism of CRNN downregulation and explore the genetic imbalances at 1q21.3 across oral squamous cell carcinoma (OSCC) samples. Materials and methods In mutation screening of CRNN gene, gDNA from...

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Bibliographic Details
Published in:	Clinical oral investigations Vol. 19; no. 9; pp. 2273 - 2283
Main Authors:	Salahshourifar, Iman, Vincent-Chong, Vui King, Chang, Hong-Yun, Ser, Hooi Leng, Ramanathan, Anand, Kallarakkal, Thomas George, Rahman, Zainal Ariff Abdul, Ismail, Siti Mazlipah, Prepageran, Narayanan, Mustafa, Wan Mahadzir Wan, Abraham, Mannil Thomas, Tay, Keng Kiong, Zain, Rosnah Binti
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01-12-2015 Springer Nature B.V
Subjects:	Carcinoma, Squamous Cell - genetics Dentistry Down-Regulation Genomic Instability Humans Immunohistochemistry Loss of Heterozygosity Malaysia Medicine Membrane Proteins - genetics Microsatellite Instability Mouth Neoplasms - genetics Neoplasm Proteins - genetics Original Article Polymerase Chain Reaction Prognosis Oral squamous cell carcinoma Genetic instability gene 1q23.1. LOH/MSI CRNN gene
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