Evaluation of the relationship between pain inflammation due to dental caries and growth parameters in preschool children

• Published in: Clinical oral investigations Vol. 27; no. 7; pp. 3721 - 3730
• Main Authors: Gunay, Basak, Kaya, Mustafa Sarp, Ozgen, Ilker Tolga, Guler, Eray Metin, Kocyigit, Abdurrahim
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01-07-2023; Springer Nature B.V
• Subjects: Body mass index; Body measurements; Child, Preschool; Children; Dental care; Dental caries; Dental Caries - therapy; Dentistry; Humans; Inflammation; Insulin; Insulin-like growth factor I; Insulin-like growth factors; Medicine; Oral Health; Oral hygiene; Pain; Pain management; Preschool children; Quality of Life; Sleep; Sleep disorders; Statistical analysis; Surveys and Questionnaires; Dental caries; ECOHIS; Growth; Child; Sleep disturbances
• ISSN: 1436-3771; 1432-6981; 1436-3771
• DOI: 10.1007/s00784-023-04988-2

Objectives
To evaluate the relationship between pain inflammation due to dental caries and growth parameters, sleep disturbances, and oral health-related quality of life (OHRQoL) in preschool children before/after dental treatment and compare the results with the control group.
Materials and methods
Study (pain inflammation due to caries) and control groups were included in this prospective clinical trial. The Child Sleep Habits Questionnaire (CSHQ) assessing sleep disturbances and the Early Childhood Oral Health Impact Scale (ECOHIS) assessing OHRQoL were applied in the corresponding time intervals to the study and control groups, respectively: baseline (T0
study
), 7 days after treatment (T1
study
), and following 6 months (T2
study
); baseline (T0
control
), and the following 6 months (T2
control
). Biochemical growth parameters (insulin-like growth factor-1 and insulin-like growth factor binding protein-3) and anthropometric measurements (standard deviation score of height, weight, and body mass index) were obtained at T0
study
, T2
study
, and T0
control
. Mann-Whitney U and the Student
t
-tests were used for statistical analyses. The significance level was set at
p
< 0.05.
Results
Data on 45 children (mean age: 55.6 ± 10.37 months) were analyzed. T2
study
was statistically higher than T0
study
for the anthropometric measurements and biochemical growth parameters (
p
< 0.05). T0
study
was statistically higher than T0
control
for biochemical growth parameters (
p
< 0.05). CSHQ and ECOHIS scores were found statistically significant at T0
study
than T0
control
(
p
< 0.05). Statistical scores of CSHQ and ECOHIS in T2
study
were significantly reduced compared to T0
study
(
p
< 0.05).
Conclusion
Children’s growth parameters, sleep disturbances, and OHRQoL improved after the elimination of pain and inflammation.
Clinical relevance
This study’s novelty is the observation of drastically increased growth parameters and reduced sleep disturbances following dental treatment.