Alterations of Glucocorticoid Receptor Gene Methylation in Externalizing Disorders During Childhood and Adolescence

Epigenetic modulations are a hypothesized link between environmental factors and the development of psychiatric disorders. Research has suggested that patients with depression or bipolar disorder exhibit higher methylation levels in the glucocorticoid receptor gene NR3C1 . We aimed to investigate wh...

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Bibliographic Details
Published in:	Behavior genetics Vol. 45; no. 5; pp. 529 - 536
Main Authors:	Heinrich, Angela, Buchmann, Arlette F., Zohsel, Katrin, Dukal, Helene, Frank, Josef, Treutlein, Jens, Nieratschker, Vanessa, Witt, Stephanie H., Brandeis, Daniel, Schmidt, Martin H., Esser, Günter, Banaschewski, Tobias, Laucht, Manfred, Rietschel, Marcella
Format:	Journal Article
Language:	English
Published:	New York Springer US 01-09-2015 Springer Nature B.V
Subjects:	Adolescent Aggressiveness Behavioral Science and Psychology Binding sites Bipolar disorder Child Child & adolescent psychiatry Child Behavior Disorders - genetics Child development Clinical Psychology Conduct disorder Depressive Disorder - genetics DNA methylation DNA Methylation - genetics Epigenetics Exons Female Health Psychology Hormones Humans Male Mental depression Mental disorders Mental health Original Research Psychology Psychotherapy Public Health Receptors, Glucocorticoid - genetics Reverse Transcriptase Polymerase Chain Reaction Stress Young Adult Germany Epigenetic Methylation Adolescents Externalizing disorders Glucocorticoid receptor
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