Increased longevity due to sexual activity in mole-rats is associated with transcriptional changes in the HPA stress axis

Sexual activity and/or reproduction are associated with a doubling of life expectancy in the long-lived rodent genus . To investigate the molecular mechanisms underlying this phenomenon, we analyzed 636 RNA-seq samples across 15 tissues. This analysis suggests that changes in the regulation of the h...

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Published in:eLife Vol. 10
Main Authors: Sahm, Arne, Platzer, Matthias, Koch, Philipp, Henning, Yoshiyuki, Bens, Martin, Groth, Marco, Burda, Hynek, Begall, Sabine, Ting, Saskia, Goetz, Moritz, Van Daele, Paul, Staniszewska, Magdalena, Klose, Jasmin Mona, Costa, Pedro Fragoso, Hoffmann, Steve, Szafranski, Karol, Dammann, Philip
Format: Journal Article
Language:English
Published: England eLife Sciences Publications Ltd 16-03-2021
eLife Sciences Publications, Ltd
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