Chronic hepatitis C liver microenvironment: role of the Th17/Treg interplay related to fibrogenesis

The role of the different lymphocyte populations in liver microenvironment of chronic hepatitis C (CHC) patients is still matter of debate. Since Th17 and Treg have opposite functions, their balance could affect disease progression. The aim was to explore liver microenvironment and its peripheral bl...

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Bibliographic Details
Published in:	Scientific reports Vol. 7; no. 1; pp. 13283 - 9
Main Authors:	Rios, Daniela Alejandra, Valva, Pamela, Casciato, Paola Cecilia, Frias, Silvia, Soledad Caldirola, María, Gaillard, María Isabel, Bezrodnik, Liliana, Bandi, Juan, Galdame, Omar, Ameigeiras, Beatriz, Krasniansky, Diana, Brodersen, Carlos, Mullen, Eduardo, Matteo, Elena Noemí De, Preciado, María Victoria
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 16-10-2017 Nature Publishing Group
Subjects:	13/1 13/31 13/51 14/19 14/63 38 38/77 692/4020/4021/234/2513/1551 692/420/2780 692/699/255/234/2513/1551 Adult Aged Biomarkers Biopsy CD4 antigen Cell Communication Cellular Microenvironment - immunology Female Fibrosis Fluorescent Antibody Technique Foxp3 protein Helper cells Hepatitis Hepatitis C Hepatitis C, Chronic - immunology Hepatitis C, Chronic - metabolism Hepatitis C, Chronic - pathology Hepatitis C, Chronic - virology Humanities and Social Sciences Humans Immunohistochemistry Immunophenotyping Interferon Interleukin 10 Interleukin 6 Liver Liver Cirrhosis - etiology Liver Cirrhosis - metabolism Liver Cirrhosis - pathology Liver Function Tests Lymphocytes Lymphocytes T Male Middle Aged multidisciplinary Pathogenesis Peripheral blood Science Science (multidisciplinary) T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - metabolism Th17 Cells - immunology Th17 Cells - metabolism Tumor necrosis factor-α Viral Load
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