Targeting dendritic cells through gold nanoparticles: A review on the cellular uptake and subsequent immunological properties

•Gold NPs as potential tool in immunotherapies due to their customizable size and shape, surface functionalization and unique optical properties.•Manipulation of gold NPs to target DCs for immunotherapies and vaccine development.•Gold NPs affect DCs maturation and their subsequent cytokine secretion...

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Bibliographic Details
Published in:	Molecular immunology Vol. 91; pp. 123 - 133
Main Authors:	Ahmad, Suhana, Zamry, Anes Ateqah, Tan, Hern-Tze Tina, Wong, Kah Keng, Lim, JitKang, Mohamud, Rohimah
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-11-2017
Subjects:	Animals Cytokine Dendritic cells Dendritic Cells - immunology Drug Delivery Systems Gold - therapeutic use Gold nanoparticles Humans Immunotherapy - methods Maturation Metal Nanoparticles - therapeutic use T cells T-Lymphocytes - immunology TCR AVNs Ag EPR AuNP MHC DLS T cells CTAB LPS Th CLRs DCs DC-SIGN mPEG CTLA-4 Zw NCs APCs rhTNF Dendritic cells Maturation Tregs Gold nanoparticles Cytokine LSPR UV-vis ER NPs PEG PLGA Teff ZwMUA CTL HSCs PVA NK TEM TLRs
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