No Evidence that Knops Blood Group Polymorphisms Affect Complement Receptor 1 Clustering on Erythrocytes

Clustering of Complement Receptor 1 (CR1) in the erythrocyte membrane is important for immune-complex transfer and clearance. CR1 contains the Knops blood group antigens, including the antithetical pairs Swain-Langley 1 and 2 (Sl1 and Sl2) and McCoy a and b (McC a and McC b ), whose functional effec...

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Bibliographic Details
Published in:	Scientific reports Vol. 7; no. 1; pp. 17825 - 13
Main Authors:	Swann, O. V., Harrison, E. M., Opi, D. H., Nyatichi, E., Macharia, A., Uyoga, S., Williams, T. N., Rowe, J. A.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 19-12-2017 Nature Publishing Group
Subjects:	14/1 14/19 14/63 631/208/248/144 631/250/2501 Antigens Blood diseases Blood Group Antigens - genetics Blood groups Child Children Cluster Analysis Complement receptors Confocal microscopy Copy number Erythrocyte Membrane - genetics Erythrocytes Erythrocytes - physiology Female Gene Dosage - genetics Genotype Genotype & phenotype Genotypes Humanities and Social Sciences Humans Immune clearance Immunofluorescence Kenya Male multidisciplinary Polymorphism, Genetic - genetics Receptors, Complement 3b - genetics Science Science (multidisciplinary) Kenya
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