Development of Molecular Magnetic Resonance Imaging Tools for Risk Stratification of Carotid Atherosclerotic Disease Using Dual-Targeted Microparticles of Iron Oxide

Identification of patients with high-risk asymptomatic carotid plaques remains a challenging but crucial step in stroke prevention. Inflammation is the key factor that drives plaque instability. Currently, there is no imaging tool in routine clinical practice to assess the inflammatory status within...

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Bibliographic Details
Published in:	Translational stroke research Vol. 13; no. 2; pp. 245 - 256
Main Authors:	Chan, Joyce M. S., Jin, Park Sung, Ng, Michael, Garnell, Joanne, Ying, Chan Wan, Tec, Chong Tze, Bhakoo, Kishore
Format:	Journal Article
Language:	English
Published:	New York Springer US 01-04-2022 Springer Nature B.V
Subjects:	Animals Apolipoproteins Asymptomatic Atherosclerosis Biomedical and Life Sciences Biomedicine Cardiology Carotid arteries Carotid Arteries - diagnostic imaging Carotid Arteries - pathology Carotid Artery Diseases - diagnostic imaging Contrast agents Endothelium Ferric Compounds Humans Inflammation Magnetic resonance imaging Magnetic Resonance Imaging - methods Mice Neurology Neurosciences Neurosurgery Original Original Article Plaque, Atherosclerotic - diagnostic imaging Plaque, Atherosclerotic - pathology Risk Assessment Shear stress Statistical analysis Stroke Stroke - pathology Thromboembolism Vascular Surgery Veins & arteries Vulnerable carotid plaques Stroke Inflammation Iron oxide particles Atherosclerosis Risk stratification
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