Environmental factors modulated ancient mitochondrial DNA variability and the prevalence of rheumatic diseases in the Basque Country

Among the factors that would explain the distribution of mitochondrial lineages in Europe, climate and diseases may have played an important role. A possible explanation lies in the nature of the mitochondrion, in which the energy generation process produces reactive oxygen species that may influenc...

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Bibliographic Details
Published in:	Scientific reports Vol. 9; no. 1; pp. 20380 - 9
Main Authors:	Laza, I. M., Hervella, M., Neira Zubieta, M., de-la-Rúa, C.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 31-12-2019 Nature Publishing Group
Subjects:	38/22 38/23 38/77 45/29 631/181/19/2471 631/181/457 631/208 704/106/413 Climate change DNA, Ancient DNA, Mitochondrial - genetics Energy efficiency Environmental factors Evolution, Molecular Genetic Predisposition to Disease Humanities and Social Sciences Humans Ice ages Low temperature Mitochondrial DNA multidisciplinary Prevalence Reactive oxygen species Rheumatic diseases Rheumatic Diseases - epidemiology Rheumatic Diseases - genetics Science Science (multidisciplinary) Spain Spondyloarthropathy Spain
Online Access:	Get full text
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