Identification of environmental factors that promote intestinal inflammation

Genome-wide association studies have identified risk loci linked to inflammatory bowel disease (IBD) 1 —a complex chronic inflammatory disorder of the gastrointestinal tract. The increasing prevalence of IBD in industrialized countries and the augmented disease risk observed in migrants who move int...

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Bibliographic Details
Published in:	Nature (London) Vol. 611; no. 7937; pp. 801 - 809
Main Authors:	Sanmarco, Liliana M., Chao, Chun-Cheih, Wang, Yu-Chao, Kenison, Jessica E., Li, Zhaorong, Rone, Joseph M., Rejano-Gordillo, Claudia M., Polonio, Carolina M., Gutierrez-Vazquez, Cristina, Piester, Gavin, Plasencia, Agustin, Li, Lucinda, Giovannoni, Federico, Lee, Hong-Gyun, Faust Akl, Camilo, Wheeler, Michael A., Mascanfroni, Ivan, Jaronen, Merja, Alsuwailm, Moneera, Hewson, Patrick, Yeste, Ada, Andersen, Brian M., Franks, Diana G., Huang, Chien-Jung, Ekwudo, Millicent, Tjon, Emily C., Rothhammer, Veit, Takenaka, Maisa, de Lima, Kalil Alves, Linnerbauer, Mathias, Guo, Lydia, Covacu, Ruxandra, Queva, Hugo, Fonseca-Castro, Pedro Henrique, Bladi, Maha Al, Cox, Laura M., Hodgetts, Kevin J., Hahn, Mark E., Mildner, Alexander, Korzenik, Joshua, Hauser, Russ, Snapper, Scott B., Quintana, Francisco J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 24-11-2022 Nature Publishing Group
Subjects:	45 45/91 631/250/38 64 64/116 64/60 692/699/1503 Animal models Animals Bioassays Biological activity CCAAT-Enhancer-Binding Protein-beta Colon Databases, Factual Dendritic cells Dendritic Cells - drug effects Dendritic Cells - immunology Dendritic Cells - metabolism Disease Disease Models, Animal Environment Environment models Environmental factors Gastrointestinal system Gastrointestinal tract Genome-wide association studies Genomes Health risks Herbicides Herbicides - adverse effects Humanities and Social Sciences Inflammation Inflammation - chemically induced Inflammation - etiology Inflammation - immunology Inflammation - pathology Inflammatory bowel disease Inflammatory bowel diseases Inflammatory Bowel Diseases - chemically induced Inflammatory Bowel Diseases - etiology Inflammatory Bowel Diseases - immunology Inflammatory Bowel Diseases - pathology Inflammatory diseases Intestine Intestines - drug effects Intestines - immunology Intestines - metabolism Intestines - pathology Large intestine Lymphocytes Lymphocytes T Machine Learning Mice Microbiota multidisciplinary NF-kappa B NF-κB protein Pathogenesis Pathology Receptors, Aryl Hydrocarbon Science Science (multidisciplinary) T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - metabolism Tumor necrosis factor-TNF Zebrafish
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