Albizzia chinensis (Osbeck) Merr extract YS ameliorates ethanol‐induced acute gastric ulcer injury in rats by regulating NRF2 signaling pathway

Background Around the world, there is a high incidence of gastric ulcers. YS, an extract from the Chinese herb Albizzia chinensis (Osbeck) Merr, has potential therapeutic applications for gastrointestinal diseases. Here we elucidated the protective effect and underlying mechanism of action of YS on...

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Bibliographic Details
Published in:	Animal models and experimental medicine Vol. 7; no. 3; pp. 275 - 282
Main Authors:	Tang, Bo, Li, Liangning, Yu, Yuanzhi, Wang, Guibin, Ma, Shuanggang, Yu, Shishan, Zhang, Jianjun
Format:	Journal Article
Language:	English
Published:	United States John Wiley & Sons, Inc 01-06-2024 John Wiley and Sons Inc Wiley
Subjects:	Alcohol use Animals Antibodies Antioxidants antioxidative Cytoplasm Drug dosages Epithelial cells Ethanol Gastric mucosa Gastric Mucosa - drug effects Gastric Mucosa - injuries Gastric Mucosa - metabolism gastric ulcer Gastrointestinal diseases Herbal medicine Hydrogen peroxide Immunoprecipitation Kelch-Like ECH-Associated Protein 1 - metabolism Laboratory animals Male Neutrophils NF-E2-Related Factor 2 - metabolism NRF2 NRF2 protein Original Oxidative stress Plant Extracts - pharmacology Plant Extracts - therapeutic use Rats Rats, Sprague-Dawley Signal transduction Signal Transduction - drug effects siRNA Statistical analysis Stomach Ulcer - chemically induced Stomach Ulcer - metabolism Themed Section: Traditional Chinese Medicines and Natural Medicines Research Therapeutic applications Ubiquitin Ubiquitination Ulcers Beijing China China YS antioxidative NRF2 gastric ulcer ethanol
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