Coupling Microfluidic Platforms, Microfabrication, and Tissue Engineered Scaffolds to Investigate Tumor Cells Mechanobiology

The tumor microenvironment (TME) is composed of dynamic and complex networks composed of matrix substrates, extracellular matrix (ECM), non-malignant cells, and tumor cells. The TME is in constant evolution during the disease progression, most notably through gradual stiffening of the stroma. Within...

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Bibliographic Details
Published in:	Micromachines (Basel) Vol. 10; no. 6; p. 418
Main Authors:	Millet, Martial, Ben Messaoud, Raoua, Luthold, Carole, Bordeleau, Francois
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 22-06-2019 MDPI
Subjects:	Adipocytes Angiogenesis Bioengineering Biology Biomechanics Cancer Cell culture Cell growth Collagen Complexity Cutting tools Cytokines disease modeling extracellular matrix Fibroblasts Growth factors In vivo methods and tests Inflammation Kinases Mechanical properties mechanobiology Metastasis microfabrication microfluidic Microfluidics New technology Review Stiffening Stiffness Substrates tumor engineered models tumor microenvironment tumor stiffness Tumorigenesis Tumors mechanobiology tumor engineered models disease modeling microfabrication tumor microenvironment microfluidic tumor stiffness extracellular matrix
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