The endothelin system mediates bone modeling in the late stage of orthodontic tooth movement in rats

Abstract The endothelin system is involved in orthodontic tooth movement (OTM). The aim of the study was to examine the role of ET-1, ETA and ETB in bone modeling during OTM in rats. Male Wistar rats ( n = 62) were divided into three groups: control animals ( n = 10; control group) without appliance...

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Bibliographic Details
Published in:	Bone (New York, N.Y.) Vol. 43; no. 4; pp. 740 - 747
Main Authors:	Sprogar, Špela, Vaupotic, Tomaz, Cör, Andrej, Drevenšek, Martina, Drevenšek, Gorazd
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Inc 01-10-2008 Elsevier Science
Subjects:	Animals Biological and medical sciences Bone modeling Bone Remodeling - drug effects Bone Remodeling - genetics Bone Remodeling - physiology Endothelin A Receptor Antagonists Endothelin system Endothelin-1 - genetics Endothelin-1 - metabolism Endothelins - genetics Endothelins - metabolism Fundamental and applied biological sciences. Psychology Immunoblotting Isoxazoles - pharmacology Male Orthodontic tooth movement Orthodontic Wires Orthopedics Osteoclast Rat Rats Rats, Wistar Receptor, Endothelin A - genetics Receptor, Endothelin A - metabolism Receptor, Endothelin B - genetics Receptor, Endothelin B - metabolism Reverse Transcriptase Polymerase Chain Reaction Skeleton and joints Sulfonamides - pharmacology Tooth Movement Techniques Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: osteoarticular system, musculoskeletal system Bone modeling Orthodontic tooth movement Osteoclast Rat Endothelin system Endothelin Rodentia Bone remodeling Vertebrata Mammalia Animal Morphology Tooth
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