Melatonin Induces Autophagy via Reactive Oxygen Species-Mediated Endoplasmic Reticulum Stress Pathway in Colorectal Cancer Cells

Even though an increasing number of anticancer treatments have been discovered, the mortality rates of colorectal cancer (CRC) have still been high in the past few years. It has been discovered that melatonin has pro-apoptotic properties and counteracts inflammation, proliferation, angiogenesis, cel...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Vol. 26; no. 16; p. 5038
Main Authors:	Chok, Kian Chung, Koh, Rhun Yian, Ng, Ming Guan, Ng, Pei Ying, Chye, Soi Moi
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 20-08-2021 MDPI
Subjects:	1-Phosphatidylinositol 3-kinase Adenosine kinase Adenosine monophosphate AKT protein Angiogenesis Antioxidants Apoptosis Autophagy Cancer therapies Cell culture Cell death Chemotherapy Colorectal cancer colorectal cancer cells Colorectal carcinoma Cytotoxicity Drug dosages Endoplasmic reticulum endoplasmic reticulum stress Gene expression Kinases Melatonin Oxidative stress Phagocytosis Protein kinase Proteins Quality of life Rapamycin reactive oxygen species TOR protein Tumors Vacuoles
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