Effects of Drugs on Exercise Performance

• Published in: Bulletin of experimental biology and medicine Vol. 155; no. 5; pp. 636 - 638
• Main Authors: Baulin, S. I., Rogacheva, S. M., Afanaseva, S. V.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01-09-2013; Springer; Springer Nature B.V
• Subjects: Administration, Oral; Animals; Animals, Outbred Strains; Antioxidants; Antioxidants - pharmacology; Biomedical and Life Sciences; Biomedicine; Cell Biology; Central Nervous System Stimulants - pharmacology; Cyclooctanes - pharmacology; Drugs; Exercise; Imidazoles - pharmacology; Internal Medicine; Laboratory Medicine; Lignans - pharmacology; Organometallic Compounds - pharmacology; Oxidative Stress - drug effects; Pathology; Physical Conditioning, Animal; Physical Endurance - drug effects; Physical Endurance - physiology; Polycyclic Compounds - pharmacology; Rats; Swimming; exercise performance; antihypoxants and antioxidants; tonics
• ISSN: 0007-4888; 1573-8221
• DOI: 10.1007/s10517-013-2213-2

The effects of 15 preparations with general tonic, antioxidant, and antihypoxant activities on exercise performance of laboratory rats were studied in the forced swimming test. The best recovery and improvement of exercise performance was recorded after a single intragastric dose of schizandrin and acyzol. These drugs stimulated an increase in the parameters in control animals by 86 and 72% (exercise performance recovery) and by 33 and 51% (exercise performance improvement).