Novel Substrates for Kinases Involved in the Biosynthesis of Inositol Pyrophosphates and Their Enhancement of ATPase Activity of a Kinase

IP6K and PPIP5K are two kinases involved in the synthesis of inositol pyrophosphates. Synthetic analogs or mimics are necessary to understand the substrate specificity of these enzymes and to find molecules that can alter inositol pyrophosphate synthesis. In this context, we synthesized four scyllo-...

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Bibliographic Details
Published in:	Molecules (Basel, Switzerland) Vol. 26; no. 12; p. 3601
Main Authors:	Mohanrao, Raja, Manorama, Ruth, Ganguli, Shubhra, Madhusudhanan, Mithun C., Bhandari, Rashna, Sureshan, Kana M.
Format:	Journal Article
Language:	English
Published:	Basel MDPI AG 11-06-2021 MDPI
Subjects:	Adenosine triphosphatase ATP ATPase Biosynthesis Enzymatic activity Enzyme activity Enzymes Inositol phosphate Inositol phosphates inositol pyrophosphate IP6K1 kinase Kinases Phosphates Phosphorylation Polyphosphates Substrate specificity Substrates VIP1 KD Yeasts
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