Bromodomain Inhibition Reveals FGF15/19 As a Target of Epigenetic Regulation and Metabolic Control

Epigenetic regulation is an important factor in glucose metabolism, but underlying mechanisms remain largely unknown. Here we investigated epigenetic control of systemic metabolism by bromodomain-containing proteins (Brds), which are transcriptional regulators binding to acetylated histone, in both...

Full description

Saved in:

Bibliographic Details
Published in:	Diabetes (New York, N.Y.) Vol. 71; no. 5; pp. 1023 - 1033
Main Authors:	Kozuka, Chisayo, Efthymiou, Vissarion, Sales, Vicencia M, Zhou, Liyuan, Osataphan, Soravis, Yuchi, Yixing, Chimene-Weiss, Jeremy, Mulla, Christopher, Isganaitis, Elvira, Desmond, Jessica, Sanechika, Suzuka, Kusuyama, Joji, Goodyear, Laurie, Shi, Xu, Gerszten, Robert E, Aguayo-Mazzucato, Cristina, Carapeto, Priscila, Teixeira, Silvania DaSilva, Sandoval, Darleen, Alonso-Curbelo, Direna, Wu, Lei, Qi, Jun, Patti, Mary-Elizabeth
Format:	Journal Article
Language:	English
Published:	United States American Diabetes Association 01-05-2022
Subjects:	Animals Diabetes Epigenesis, Genetic Epigenetics Fibroblast growth factors Fibroblast Growth Factors - metabolism Glucose Glucose metabolism Glucose tolerance Histones Hyperglycemia Ileum Insulin Insulin secretion Intestine Intolerance Liver Metabolism Mice Nuclear Proteins - genetics Nuclear Proteins - metabolism Pathophysiology Small intestine Transcription Transcription Factors - genetics Transcription Factors - metabolism
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!