Web-based surveillance of respiratory infection outbreaks: retrospective analysis of Italian COVID-19 epidemic waves using Google Trends

• Published in: Frontiers in public health Vol. 11; p. 1141688
• Main Authors: Porcu, Gloria, Chen, Yu Xi, Bonaugurio, Andrea Stella, Villa, Simone, Riva, Leonardo, Messina, Vincenzina, Bagarella, Giorgio, Maistrello, Mauro, Leoni, Olivia, Cereda, Danilo, Matone, Fulvio, Gori, Andrea, Corrao, Giovanni
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 18-05-2023
• Subjects: autoregressive moving average; COVID-19; COVID-19 - epidemiology; Disease Outbreaks; epidemic wave; Epidemics; exponentially weighted moving average control chart; Google Trends; Humans; Internet; Italy - epidemiology; Public Health; Respiratory Tract Infections - epidemiology; Retrospective Studies; Search Engine; syndromic surveillance; Italy; COVID-19; Google Trends; exponentially weighted moving average control chart; autoregressive moving average; syndromic surveillance; epidemic wave
• ISSN: 2296-2565; 2296-2565
• DOI: 10.3389/fpubh.2023.1141688

Large-scale diagnostic testing has been proven insufficient to promptly monitor the spread of the Coronavirus disease 2019. Electronic resources may provide better insight into the early detection of epidemics. We aimed to retrospectively explore whether the Google search volume has been useful in detecting Severe Acute Respiratory Syndrome Coronavirus outbreaks early compared to the swab-based surveillance system.
The Google Trends website was used by applying the research to three Italian regions (Lombardy, Marche, and Sicily), covering 16 million Italian citizens. An autoregressive-moving-average model was fitted, and residual charts were plotted to detect outliers in weekly searches of five keywords. Signals that occurred during periods labelled as free from epidemics were used to measure Positive Predictive Values and False Negative Rates in anticipating the epidemic wave occurrence.
Signals from "fever," "cough," and "sore throat" showed better performance than those from "loss of smell" and "loss of taste." More than 80% of true epidemic waves were detected early by the occurrence of at least an outlier signal in Lombardy, although this implies a 20% false alarm signals. Performance was poorer for Sicily and Marche.
Monitoring the volume of Google searches can be a valuable tool for early detection of respiratory infectious disease outbreaks, particularly in areas with high access to home internet. The inclusion of web-based syndromic keywords is promising as it could facilitate the containment of COVID-19 and perhaps other unknown infectious diseases in the future.