Proteomic but not enzyme-linked immunosorbent assay technology detects amniotic fluid monomeric calgranulins from their complexed calprotectin form

Four proteomic biomarkers (human neutrophil peptide 1 [HNP1], HNP2 [defensins], calgranulin C [Cal-C], and Cal-A) characterize the fingerprint of intra-amniotic inflammation (IAI). We compared proteomic technology using surfaced-enhanced laser desorption-ionization-time of flight (SELDI-TOF) mass sp...

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Bibliographic Details

Published in:	Clinical and diagnostic laboratory immunology Vol. 12; no. 7; pp. 837 - 844
Main Authors:	Buhimschi, Irina A, Buhimschi, Catalin S, Weiner, Carl P, Kimura, Tatsuji, Hamar, Benjamin D, Sfakianaki, Anna K, Norwitz, Errol R, Funai, Edmund F, Ratner, Elena
Format:	Journal Article
Language:	English
Published:	United States American Society for Microbiology 01-07-2005
Subjects:	Amniotic Fluid - metabolism Antibodies and Mediators of Immunity Biomarkers - analysis Calgranulin B - analysis Chorioamnionitis - metabolism Defensins - analysis Female Humans Mass Spectrometry Pregnancy Proteomics - methods Sensitivity and Specificity
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