Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation

Autoinflammatory diseases are characterized by dysregulation of innate immune system leading to spontaneous sterile inflammation. One of the well-established animal models of this group of disorders is the mouse strain . In this strain, the loss of adaptor protein PSTPIP2 leads to the autoinflammato...

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Bibliographic Details
Published in:	Frontiers in immunology Vol. 13; p. 1035226
Main Authors:	Pavliuchenko, Nataliia, Duric, Iris, Kralova, Jarmila, Fabisik, Matej, Spoutil, Frantisek, Prochazka, Jan, Kasparek, Petr, Pokorna, Jana, Skopcova, Tereza, Sedlacek, Radislav, Brdicka, Tomas
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 20-12-2022
Subjects:	Adaptor Proteins, Signal Transducing - metabolism Animals autoinflammation chronic multifocal osteomyelitis Cytoskeletal Proteins - metabolism Immunology Inflammation Mice Neutrophils PEST-family phosphatases PSTPIP2 Reactive Oxygen Species - metabolism SHIP1 autoinflammation PEST-family phosphatases PSTPIP2 neutrophils SHIP1 chronic multifocal osteomyelitis
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