Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in the current COVID-19 pandemic. Worldwide this disease has infected over 2.5 million individuals with a mortality rate ranging from 5 to 10%. There are several efforts going on in the drug discovery to control the...

Full description

Saved in:

Bibliographic Details
Published in:	Journal of biomolecular structure & dynamics Vol. 39; no. 9; pp. 3099 - 3114
Main Authors:	Joshi, Rakesh S., Jagdale, Shounak S., Bansode, Sneha B., Shankar, S. Shiva, Tellis, Meenakshi B., Pandya, Vaibhav Kumar, Chugh, Anita, Giri, Ashok P., Kulkarni, Mahesh J.
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 13-06-2021
Subjects:	Coronavirus COVID-19 hACE-2 Humans Ligands MPro multi-target-directed ligand Pandemics Peptide Hydrolases Pharmaceutical Preparations Phylogeny protease inhibitor Protease Inhibitors - pharmacology RdRp SARS-CoV-2 SARS-CoV-2 virus COVID-19 protease inhibitor Coronavirus MPro RdRp SARS-CoV-2 virus hACE-2 multi-target-directed ligand
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!