Impact of a negative prior stress test on emergency physician disposition decision in ED patients with chest pain syndromes

• Published in: The American journal of emergency medicine Vol. 25; no. 1; pp. 39 - 44
• Main Authors: Nerenberg, Rebecca H., BS, Shofer, Frances S., PhD, Robey, Jennifer L., RN, BSN, Brown, Aaron M., BS, Hollander, Judd E., MD
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Elsevier Inc 2007; Elsevier; Elsevier Limited
• Subjects: Analgesics; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Cardiovascular disease; Chest Pain - diagnosis; Chest Pain - physiopathology; Computed tomography; Coronary Disease - diagnosis; Coronary Disease - physiopathology; Decision making; Emergency; Emergency and intensive care: techniques, logistics; Emergency medical care; Emergency medical services; Emergency Service, Hospital; Exercise Test; Female; Heart attacks; Hospitals; Humans; Intensive care medicine; Intensive care unit. Emergency transport systems. Emergency, hospital ward; Male; Medical sciences; Middle Aged; Myocardial infarction; Neuropharmacology; Pain; Pharmacology. Drug treatments; Prospective Studies; Regulation of financial institutions; Stress; Human; Intensive care; Pain; Physician; Emergency; Decision; Resuscitation; Stress
• ISSN: 0735-6757; 1532-8171
• DOI: 10.1016/j.ajem.2006.05.027

Abstract Objective Many emergency department (ED) patients with potential acute coronary syndromes (ACS) have prior visits and prior cardiac testing; however, the effect of knowledge of prior testing on the emergency physician disposition decision making is not known. We studied the impact of prior noninvasive testing (ie, stress testing) for myocardial ischemia on disposition decision making in ED patients with potential ACS. Methods We performed a prospective cohort study of ED patients with chest pain who received an electrocardiogram for potential ACS. Data included demographics, medical history, stress test history, and TIMI risk score. Patients were followed in-house; 30-day telephone interviews were performed for follow-up. Main outcomes were ED disposition (admit/discharge) and a composite of 30-day death, acute myocardial infarction, and revascularization stratified on the basis of prior stress testing known at the time of presentation. Standard statistical techniques were used with 95% confidence intervals (CI). Results There were 1853 patients enrolled and 97% had follow-up. Patients had a mean age of 53 ± 14 years; 60% were women, 67% were black. There were 1491 (79%) patients without a prior stress test, 291 (16%) had a normal prior stress test result, and 89 (5%) had an abnormal prior stress test result. Admission rates were 92% (95% CI, 87%-98%) for patients with a prior abnormal stress test, 73% (95% CI, 67%-78%) for patients with a normal prior stress test, and 70% (95% CI, 67%-72%) for patients without a prior stress test. Adverse outcomes were the highest among patients with prior abnormal stress test but did not differ significantly between patients with no prior stress test and patients with prior normal stress test (10.1% [95% CI, 3.6-16.7%] vs 5.2% [95% CI, 4.1-6.4%] vs 4.8% [95% CI, 2.4-7.3%]). Conclusion Patients without prior stress tests and patients with prior normal stress tests were admitted for potential ACS at the same rate and had the same 30-day cardiovascular event rates. This suggests that prior stress testing does not affect subsequent disposition decisions. Perhaps cardiac catheterization or computed tomography coronary angiograms would have more of an impact on subsequent visits, making them potentially more cost-effective in the low-risk patient.