Catalase Influence in the Regulation of Coronary Resistance by Estrogen: Joint Action of Nitric Oxide and Hydrogen Peroxide
We tested the influence of estrogen on coronary resistance regulation by modulating nitric oxide (NO) and hydrogen peroxide (H2O2) levels in female rats. For this, estrogen levels were manipulated and the hearts were immediately excised and perfused at a constant flow using a Langendorff’s apparatus...
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| Published in: | Oxidative medicine and cellular longevity Vol. 2014; no. 2014; pp. 1 - 6 |
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Cairo, Egypt
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01-01-2014
John Wiley & Sons, Inc |
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| Abstract | We tested the influence of estrogen on coronary resistance regulation by modulating nitric oxide (NO) and hydrogen peroxide (H2O2) levels in female rats. For this, estrogen levels were manipulated and the hearts were immediately excised and perfused at a constant flow using a Langendorff’s apparatus. Higher estrogen levels were associated with a lower coronary resistance, increased nitric oxide bioavailability, and higher levels of H2O2. When oxide nitric synthase blockade by L-NAME was performed, no significant changes were found in coronary resistance of ovariectomized rats. Additionally, we found an inverse association between NO levels and catalase activity. Taken together, our data suggest that, in the absence of estrogen influence and, therefore, reduced NO bioavailability, coronary resistance regulation seems to be more dependent on the H2O2 that is maintained at low levels by increased catalase activity. |
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| AbstractList | We tested the influence of estrogen on coronary resistance regulation by modulating nitric oxide (NO) and hydrogen peroxide (H2O2) levels in female rats. For this, estrogen levels were manipulated and the hearts were immediately excised and perfused at a constant flow using a Langendorff’s apparatus. Higher estrogen levels were associated with a lower coronary resistance, increased nitric oxide bioavailability, and higher levels of H2O2. When oxide nitric synthase blockade by L-NAME was performed, no significant changes were found in coronary resistance of ovariectomized rats. Additionally, we found an inverse association between NO levels and catalase activity. Taken together, our data suggest that, in the absence of estrogen influence and, therefore, reduced NO bioavailability, coronary resistance regulation seems to be more dependent on the H2O2 that is maintained at low levels by increased catalase activity. We tested the influence of estrogen on coronary resistance regulation by modulating nitric oxide (NO) and hydrogen peroxide (H 2 O 2 ) levels in female rats. For this, estrogen levels were manipulated and the hearts were immediately excised and perfused at a constant flow using a Langendorff’s apparatus. Higher estrogen levels were associated with a lower coronary resistance, increased nitric oxide bioavailability, and higher levels of H 2 O 2 . When oxide nitric synthase blockade by L-NAME was performed, no significant changes were found in coronary resistance of ovariectomized rats. Additionally, we found an inverse association between NO levels and catalase activity. Taken together, our data suggest that, in the absence of estrogen influence and, therefore, reduced NO bioavailability, coronary resistance regulation seems to be more dependent on the H 2 O 2 that is maintained at low levels by increased catalase activity. |
| Audience | Academic |
| Author | Belló-Klein, Adriane Fernandes, Tânia R. G. Campos, Cristina Fernandes, Rafael O. Araujo, Alex Sander da Rosa Viegas, Vinícius U. Schenkel, Paulo C. |
| AuthorAffiliation | Laboratório de Fisiologia Cardiovascular, Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Sarmento Leite 500, Bairro Farroupilha, 90050-170 Porto Alegre, RS, Brazil |
| AuthorAffiliation_xml | – name: Laboratório de Fisiologia Cardiovascular, Departamento de Fisiologia, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Sarmento Leite 500, Bairro Farroupilha, 90050-170 Porto Alegre, RS, Brazil |
| Author_xml | – sequence: 1 fullname: Belló-Klein, Adriane – sequence: 2 fullname: Fernandes, Tânia R. G. – sequence: 3 fullname: Campos, Cristina – sequence: 4 fullname: Viegas, Vinícius U. – sequence: 5 fullname: Fernandes, Rafael O. – sequence: 6 fullname: Schenkel, Paulo C. – sequence: 7 fullname: Araujo, Alex Sander da Rosa |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24669281$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1016_j_lfs_2022_120917 crossref_primary_10_1007_s11356_015_5494_3 crossref_primary_10_3390_cimb46030127 crossref_primary_10_1080_13813455_2020_1779752 crossref_primary_10_1159_000368606 |
| Cites_doi | 10.1152/ajpregu.1998.274.4.R970 10.1016/j.pharmthera.2012.03.007 10.1056/NEJM199906103402306 10.1016/S0076-6879(84)05016-3 10.1161/01.CIR.96.2.667 10.5625/lar.2012.28.2.71 10.1016/0027-5107(85)90216-7 10.1111/j.1432-1033.1995.tb20798.x 10.1161/01.RES.64.1.43 10.1089/152308601750100443 10.1023/B:NERE.0000042219.98446.e7 10.4330/wjc.v3.i6.186 10.1177/030089168507100305 10.1530/eje.0.1480281 10.1152/ajpheart.2000.279.6.H2766 10.1152/ajpheart.00187.2006 10.1016/S0021-9258(19)52451-6 10.1590/S1807-59322010000100015 10.1016/S0021-9258(18)35745-4 10.1007/s12012-008-9022-2 10.1007/s00395-003-0408-9 10.1152/ajpheart.01342.2006 10.1124/mol.63.2.325 10.1161/STROKEAHA.106.477406 10.1161/01.ATV.21.4.496 10.1016/j.steroids.2004.09.008 10.1016/j.yjmcc.2004.04.012 10.1111/j.1472-8206.2010.00923.x 10.1016/S0076-6879(99)01068-X 10.1002/cbf.1616 10.1016/0022-1759(80)90340-3 10.1111/j.1472-8206.2010.00911.x 10.1016/j.yjmcc.2006.10.007 |
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| Copyright | Copyright © 2014 Paulo C. Schenkel et al. COPYRIGHT 2014 John Wiley & Sons, Inc. Copyright © 2014 Paulo C. Schenkel et al. 2014 |
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| Notes | Academic Editor: Neelam Khaper |
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| References | (4) 2011; 3 (21) 1998; 301 (23) 1985; 148 (2) 2010; 65 (14) 2007; 42 (29) 1998; 274 (15) 2004; 69 (25) 1951; 193 (28) 2007; 293 (34) 2012; 26 (9) 2001; 3 (24) 1984; 105 (10) 2006; 291 (3) 2003; 148 (11) 2001; 21 (20) 1985; 71 (8) 1997; 96 (7) 1992; 267 (13) 2000; 279 (30) 2003; 63 (18) 2010; 28 (22) 1980; 38 (33) 2007; 38 (19) 2003; 98 (6) 1989; 64 (27) 2012; 135 (5) 2009; 15 (17) 2002; 62 (35) 1995; 232 (31) 2004; 37 (26) 2012; 28 (12) 2008; 8 (1) 1999; 340 (16) 2004; 29 (32) 2012; 26 18683081 - Cardiovasc Toxicol. 2008 Fall;8(3):101-13 6778929 - J Immunol Methods. 1980;38(1-2):161-70 20126352 - Clinics (Sao Paulo). 2010;65(1):99-106 22787479 - Lab Anim Res. 2012 Jun;28(2):71-6 12527803 - Mol Pharmacol. 2003 Feb;63(2):325-31 9244241 - Circulation. 1997 Jul 15;96(2):667-75 17141266 - J Mol Cell Cardiol. 2007 Jan;42(1):79-87 6727660 - Methods Enzymol. 1984;105:121-6 3861023 - Tumori. 1985 Jun 30;71(3):241-9 14907713 - J Biol Chem. 1951 Nov;193(1):265-75 9575958 - Am J Physiol. 1998 Apr;274(4 Pt 2):R970-8 16648191 - Am J Physiol Heart Circ Physiol. 2006 Sep;291(3):H1138-46 17525399 - Stroke. 2007 Jul;38(7):2142-9 15582532 - Steroids. 2004 Dec;69(13-14):779-87 19789524 - Med Sci Monit. 2009 Oct;15(10):RA209-219 17351066 - Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H314-21 21226757 - Fundam Clin Pharmacol. 2012 Apr;26(2):235-49 7556149 - Eur J Biochem. 1995 Aug 15;232(1):188-91 19885851 - Cell Biochem Funct. 2010 Jan;28(1):38-44 3969077 - Mutat Res. 1985 Jan-Feb;148(1-2):129-34 11304463 - Arterioscler Thromb Vasc Biol. 2001 Apr;21(4):496-502 2535797 - Circ Res. 1989 Jan;64(1):43-54 12883834 - Basic Res Cardiol. 2003 May;98(3):165-74 11087231 - Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2766-75 22484805 - Pharmacol Ther. 2012 Jul;135(1):54-70 12659010 - Braz J Biol. 2002 Nov;62(4A):609-14 21210847 - Fundam Clin Pharmacol. 2012 Apr;26(2):219-26 21772945 - World J Cardiol. 2011 Jun 26;3(6):186-200 9919553 - Methods Enzymol. 1999;301:49-61 11294189 - Antioxid Redox Signal. 2001 Feb;3(1):11-22 15242742 - J Mol Cell Cardiol. 2004 Jul;37(1):121-5 12611608 - Eur J Endocrinol. 2003 Mar;148(3):281-92 1280257 - J Biol Chem. 1992 Dec 5;267(34):24173-6 10362825 - N Engl J Med. 1999 Jun 10;340(23):1801-11 15532548 - Neurochem Res. 2004 Oct;29(10):1923-30 24 26 27 28 30 31 10 32 33 12 34 35 14 15 16 18 1 2 3 4 21 |
| References_xml | – volume: 28 start-page: 71 year: 2012 end-page: 76 ident: 26 article-title: Functions and physiological roles of two types of estrogen receptors, ERalpha and ERbeta, identified by estrogen receptor knockout mouse publication-title: – volume: 69 start-page: 779 issue: 13-14 year: 2004 end-page: 787 ident: 15 article-title: Treatment with 17- -estradiol reduces superoxide production in aorta of ovariectomized rats publication-title: – volume: 301 start-page: 49 year: 1998 end-page: 61 ident: 21 article-title: Measuring nitric oxide production in human clinical studies publication-title: – volume: 96 start-page: 667 issue: 2 year: 1997 end-page: 675 ident: 8 article-title: L-arginine treatment alters the kinetics of nitric oxide and superoxide release and reduces ischemia/reperfusion injury in skeletal muscle publication-title: – volume: 65 start-page: 99 issue: 1 year: 2010 end-page: 106 ident: 2 article-title: Coronary heart disease in women: a challenge for the 21st century publication-title: – volume: 267 start-page: 24173 issue: 34 year: 1992 end-page: 24176 ident: 7 article-title: Generation of superoxide by purified brain nitric oxide synthase publication-title: – volume: 3 start-page: 11 issue: 1 year: 2001 end-page: 22 ident: 9 article-title: Nitric oxide and peroxynitrite in postischemic myocardium publication-title: – volume: 62 start-page: 609 issue: 4 year: 2002 end-page: 614 ident: 17 article-title: Determination of the estrous cycle phases of rats: some helpful considerations publication-title: – volume: 38 start-page: 2142 issue: 7 year: 2007 end-page: 2149 ident: 33 article-title: Effect of gender on NADPH-oxidase activity, expression, and function in the cerebral circulation: role of estrogen publication-title: – volume: 3 start-page: 186 year: 2011 end-page: 200 ident: 4 article-title: Ischemia/reperfusion injury and cardioprotective mechanisms: role of mitochondria and reactive oxygen species publication-title: – volume: 105 start-page: 121 year: 1984 end-page: 126 ident: 24 article-title: Catalase in vitro publication-title: – volume: 291 start-page: H1138 issue: 3 year: 2006 end-page: H1146 ident: 10 article-title: Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo publication-title: – volume: 29 start-page: 1923 issue: 10 year: 2004 end-page: 1930 ident: 16 article-title: Estradiol protects against oxidative stress induced by chronic variate stress publication-title: – volume: 135 start-page: 54 year: 2012 end-page: 70 ident: 27 article-title: Estrogen and the cardiovascular system publication-title: – volume: 232 start-page: 188 issue: 1 year: 1995 end-page: 191 ident: 35 article-title: Reversible binding and inhibition of catalase by nitric oxide publication-title: – volume: 8 start-page: 101 issue: 3 year: 2008 end-page: 113 ident: 12 article-title: Estrogen-mediated protection in myocardial ischemia-reperfusion injury publication-title: – volume: 15 start-page: RA209 issue: 10 year: 2009 end-page: RA219 ident: 5 article-title: Oxidative stress and ischemic myocardial syndromes publication-title: – volume: 38 start-page: 161 issue: 1-2 year: 1980 end-page: 170 ident: 22 article-title: A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture publication-title: – volume: 193 start-page: 265 issue: 1 year: 1951 end-page: 275 ident: 25 article-title: Protein measurement with the Folin phenol reagent publication-title: – volume: 293 start-page: H314 issue: 1 year: 2007 end-page: H321 ident: 28 article-title: Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling publication-title: – volume: 340 start-page: 1801 issue: 23 year: 1999 end-page: 1811 ident: 1 article-title: The protective effects of estrogen on the cardiovascular system publication-title: – volume: 37 start-page: 121 issue: 1 year: 2004 end-page: 125 ident: 31 article-title: Oscillatory shear stress upregulation of endothelial nitric oxide synthase requires intracellular hydrogen peroxide and CaMKII publication-title: – volume: 148 start-page: 281 issue: 3 year: 2003 end-page: 292 ident: 3 article-title: Non-genomic actions of sex steroid hormones publication-title: – volume: 21 start-page: 496 issue: 4 year: 2001 end-page: 502 ident: 11 article-title: Reactive oxygen species mediate endothelium-dependent relaxations in Tetrahydrobiopterin-deficient mice publication-title: – volume: 64 start-page: 43 issue: 1 year: 1989 end-page: 54 ident: 6 article-title: Impaired canine coronary vasodilator response to acetylcholine and bradykinin after occlusion-reperfusion publication-title: – volume: 42 start-page: 79 issue: 1 year: 2007 end-page: 87 ident: 14 article-title: Pharmacological postconditioning with the phytoestrogen genistein publication-title: – volume: 26 start-page: 235 issue: 2 year: 2012 end-page: 249 ident: 34 article-title: Increased blood oxidative stress in experimental menopause rat model: the effects of vitamin A low-dose supplementation upon antioxidant status in bilateral ovariectomized rats publication-title: – volume: 274 start-page: R970 issue: 4 year: 1998 end-page: R978 ident: 29 article-title: Hemodynamic effect of 17 -estradiol in absence of NO in ovariectomized rats: role of angiotensin II publication-title: – volume: 279 start-page: H2766 issue: 6 year: 2000 end-page: H2775 ident: 13 article-title: Effect of estrogen on global myocardial ischemia-reperfusion injury in female rats publication-title: – volume: 148 start-page: 129 issue: 1-2 year: 1985 end-page: 134 ident: 23 article-title: Superoxide dismutase isoenzymes in tissues and plasma from New Zealand black mice, nude mice and normal BALB/c mice publication-title: – volume: 26 start-page: 219 issue: 2 year: 2012 end-page: 226 ident: 32 article-title: Diverse modulating effects of estradiol and progesterone on the monophasic action potential duration in Langendorff-perfused female rabbit hearts publication-title: – volume: 28 start-page: 38 issue: 1 year: 2010 end-page: 44 ident: 18 article-title: Increased resistance to hydrogen peroxide-induced cardiac contracture is associated with decreased myocardial oxidative stress in hypothyroid rats publication-title: – volume: 71 start-page: 241 issue: 3 year: 1985 end-page: 249 ident: 20 article-title: Comparison of lipid peroxidation and myocardial damage induced by adriamycin and 4′-epiadriamycin in mice publication-title: – volume: 98 start-page: 165 issue: 3 year: 2003 end-page: 174 ident: 19 article-title: Selective modulation of endogenous nitric oxide formation in ischemia/reperfusion injury in isolated rat hearts: effects on regional myocardial flow and enzyme release publication-title: – volume: 63 start-page: 325 issue: 2 year: 2003 end-page: 331 ident: 30 article-title: Akt-dependent phosphorylation of serine 1179 and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase 1/2 cooperatively mediate activation of the endothelial nitric-oxide synthase by hydrogen peroxide publication-title: – volume: 274 start-page: R970 issue: 4 year: 1998 ident: 29 publication-title: The American Journal of Physiology—Regulatory Integrative and Comparative Physiology doi: 10.1152/ajpregu.1998.274.4.R970 – ident: 27 doi: 10.1016/j.pharmthera.2012.03.007 – ident: 1 doi: 10.1056/NEJM199906103402306 – ident: 24 doi: 10.1016/S0076-6879(84)05016-3 – volume: 96 start-page: 667 issue: 2 year: 1997 ident: 8 publication-title: Circulation doi: 10.1161/01.CIR.96.2.667 – ident: 26 doi: 10.5625/lar.2012.28.2.71 – volume: 148 start-page: 129 issue: 1-2 year: 1985 ident: 23 publication-title: Mutation Research doi: 10.1016/0027-5107(85)90216-7 – ident: 35 doi: 10.1111/j.1432-1033.1995.tb20798.x – volume: 64 start-page: 43 issue: 1 year: 1989 ident: 6 publication-title: Circulation Research doi: 10.1161/01.RES.64.1.43 – volume: 3 start-page: 11 issue: 1 year: 2001 ident: 9 publication-title: Antioxidants and Redox Signaling doi: 10.1089/152308601750100443 – ident: 16 doi: 10.1023/B:NERE.0000042219.98446.e7 – volume: 62 start-page: 609 issue: 4 year: 2002 ident: 17 publication-title: Brazilian Journal of Biology – ident: 4 doi: 10.4330/wjc.v3.i6.186 – volume: 71 start-page: 241 issue: 3 year: 1985 ident: 20 publication-title: Tumori doi: 10.1177/030089168507100305 – ident: 3 doi: 10.1530/eje.0.1480281 – volume: 279 start-page: H2766 issue: 6 year: 2000 ident: 13 publication-title: The American Journal of Physiology—Heart and Circulatory Physiology doi: 10.1152/ajpheart.2000.279.6.H2766 – ident: 10 doi: 10.1152/ajpheart.00187.2006 – volume: 193 start-page: 265 issue: 1 year: 1951 ident: 25 publication-title: The Journal of Biological Chemistry doi: 10.1016/S0021-9258(19)52451-6 – ident: 2 doi: 10.1590/S1807-59322010000100015 – volume: 267 start-page: 24173 issue: 34 year: 1992 ident: 7 publication-title: Journal of Biological Chemistry doi: 10.1016/S0021-9258(18)35745-4 – ident: 12 doi: 10.1007/s12012-008-9022-2 – volume: 98 start-page: 165 issue: 3 year: 2003 ident: 19 publication-title: Basic Research in Cardiology doi: 10.1007/s00395-003-0408-9 – ident: 28 doi: 10.1152/ajpheart.01342.2006 – volume: 15 start-page: RA209 issue: 10 year: 2009 ident: 5 publication-title: Medical Science Monitor – ident: 30 doi: 10.1124/mol.63.2.325 – ident: 33 doi: 10.1161/STROKEAHA.106.477406 – volume: 21 start-page: 496 issue: 4 year: 2001 ident: 11 publication-title: Arteriosclerosis, Thrombosis, and Vascular Biology doi: 10.1161/01.ATV.21.4.496 – ident: 15 doi: 10.1016/j.steroids.2004.09.008 – ident: 31 doi: 10.1016/j.yjmcc.2004.04.012 – ident: 34 doi: 10.1111/j.1472-8206.2010.00923.x – ident: 21 doi: 10.1016/S0076-6879(99)01068-X – ident: 18 doi: 10.1002/cbf.1616 – volume: 38 start-page: 161 issue: 1-2 year: 1980 ident: 22 publication-title: Journal of Immunological Methods doi: 10.1016/0022-1759(80)90340-3 – ident: 32 doi: 10.1111/j.1472-8206.2010.00911.x – ident: 14 doi: 10.1016/j.yjmcc.2006.10.007 |
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| Snippet | We tested the influence of estrogen on coronary resistance regulation by modulating nitric oxide (NO) and hydrogen peroxide (H2O2) levels in female rats. For... We tested the influence of estrogen on coronary resistance regulation by modulating nitric oxide (NO) and hydrogen peroxide (H 2 O 2 ) levels in female rats.... |
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| SubjectTerms | Abnormalities Animals Antioxidants - metabolism Body Weight - drug effects Cardiopulmonary system Cardiovascular system Catalase - metabolism Coronary Vessels - drug effects Coronary Vessels - enzymology Coronary Vessels - pathology Estrogen Estrogens - pharmacology Female Health aspects Hydrogen peroxide Hydrogen Peroxide - metabolism In Vitro Techniques Myocardial Contraction - drug effects Myocardium - enzymology Myocardium - pathology Nitrates - metabolism Nitric Oxide - metabolism Nitrites - metabolism Perfusion Pressure Properties Rats Rats, Wistar |
| Title | Catalase Influence in the Regulation of Coronary Resistance by Estrogen: Joint Action of Nitric Oxide and Hydrogen Peroxide |
| URI | https://search.emarefa.net/detail/BIM-1046950 https://dx.doi.org/10.1155/2014/159852 https://www.ncbi.nlm.nih.gov/pubmed/24669281 https://pubmed.ncbi.nlm.nih.gov/PMC3941593 |
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