Intraportal Infusion of Bone Marrow Mononuclear or CD133+ Cells in Patients With Decompensated Cirrhosis: A Double‐Blind Randomized Controlled Trial

The present study assessed the effects of intraportal infusions of autologous bone marrow‐derived mononuclear cells (MNCs) and/or CD133+ cells on liver function in patients with decompensated cirrhosis. We randomly assigned 27 eligible patients to a placebo, MNCs, and/or CD133+ cells. Cell infusions...

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Bibliographic Details
Published in:	Stem cells translational medicine Vol. 5; no. 1; pp. 87 - 94
Main Authors:	Mohamadnejad, Mehdi, Vosough, Massoud, Moossavi, Shirin, Nikfam, Sepideh, Mardpour, Soura, Akhlaghpoor, Shahram, Ashrafi, Mandana, Azimian, Vajiheh, Jarughi, Neda, Hosseini, Seyedeh-Esmat, Moeininia, Fatemeh, Bagheri, Mohamad, Sharafkhah, Maryam, Aghdami, Nasser, Malekzadeh, Reza, Baharvand, Hossein
Format:	Journal Article
Language:	English
Published:	Durham, NC, USA AlphaMed Press 01-01-2016 Oxford University Press
Subjects:	AC133 Antigen Administrative support Adult Aged Antigens, CD Autografts Bias Bone marrow Bone Marrow Transplantation Cell-based therapy Cirrhosis Data analysis Double-Blind Method Double-blind studies End Stage Liver Disease - pathology End Stage Liver Disease - physiopathology End Stage Liver Disease - therapy Esophagus Fibrosis - pathology Fibrosis - physiopathology Fibrosis - therapy Glycoproteins Hematopoietic stem cell Hepatitis Hepatocellular carcinoma Hepatocytes Humans Hypertension Leukocyte Transfusion Leukocytes (mononuclear) Leukocytes, Mononuclear - transplantation Liver cirrhosis Liver diseases Liver transplantation Male Middle Aged Patients Peptides Regenerative medicine Research centers Stem cells Studies Tissue Engineering and Regenerative Medicine Transplants & implants Ultrasonic imaging Iran Cirrhosis Cell-based therapy Hematopoietic stem cell Regenerative medicine
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