Successful multidisciplinary treatment of uterine serous carcinoma in a patient who had previously undergone renal transplantation

• Published in: Taiwanese journal of obstetrics & gynecology Vol. 57; no. 4; pp. 601 - 604
• Main Authors: Chiu, I-Heng, Ho, Wan-Jing, Wu, Ren-Chin, Chao, Angel
• Format: Journal Article
• Language: English
• Published: China (Republic : 1949- ) Elsevier B.V 01-08-2018; Elsevier
• Subjects: CA-125 Antigen - blood; Cystadenocarcinoma, Serous - diagnosis; Cystadenocarcinoma, Serous - surgery; Cystadenocarcinoma, Serous - therapy; Diabetes Mellitus, Type 2 - complications; Female; Heart Failure - complications; Humans; Hypertension - complications; Hysterectomy; Interdisciplinary Communication; Kidney Transplantation; Middle Aged; Multidisciplinary approach; Obesity - complications; Ovariectomy; Postmenopause; Postoperative Complications; Pulmonary Edema - complications; Renal transplant; Salpingectomy; Shock, Cardiogenic - complications; Uterine Neoplasms - diagnosis; Uterine Neoplasms - surgery; Uterine Neoplasms - therapy; Uterine serous carcinoma; Renal transplant; USC; MR; Uterine serous carcinoma; Multidisciplinary approach; LVEF; ICU; CVP; TR
• ISSN: 1028-4559; 1875-6263
• DOI: 10.1016/j.tjog.2018.06.023

Renal transplantation is a risk factor for premalignant and malignant changes of the endometrium. Thus, prompt and aggressive treatment of postoperative complications remains a major issue. We report the case of an asymptomatic postmenopausal woman with a history of renal transplantation who underwent surgery for uterine serous carcinoma (USC).
An asymptomatic 59-year-old woman who had undergone renal transplantation presented with elevated serum CA-125 levels. Cancer screening revealed uterine serous carcinoma, for which she underwent total hysterectomy and bilateral salpingo-oophorectomy. Unfortunately, the postoperative course was complicated by cardiogenic shock and decompensated heart failure. The complexities of the cardiac problems and renal transplantation required a multidisciplinary approach involving different specialists. She was successfully discharged 48 days after the surgery.
Gynecologic cancer screening in asymptomatic postmenopausal women after renal transplantation is warranted. If postoperative complications occur in this population, a multidisciplinary approach is recommended.