Histoplasma capsulatum in the bone marrow of an HIV-infected patient

•Histoplasmosis is one of the differential diagnoses for pancytopenia in HIV-infected patients.•Histoplasma capsulatum yeasts can be identified on analysis of bone marrow aspirate.•Urinary antigen testing has a high sensitivity in immunocompromised patients.•Amphotericin B is the primary therapy for...

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Bibliographic Details
Published in:International journal of infectious diseases Vol. 62; no. C; pp. 6 - 7
Main Authors: Medina-Piñón, Isaí, Hernández-Rodríguez, Pedro, Haces-Rodríguez, Silvia Estela, Acosta-Calderón, Luis Arturo
Format: Journal Article
Language:English
Published: Canada Elsevier Ltd 01-09-2017
Elsevier
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Summary:•Histoplasmosis is one of the differential diagnoses for pancytopenia in HIV-infected patients.•Histoplasma capsulatum yeasts can be identified on analysis of bone marrow aspirate.•Urinary antigen testing has a high sensitivity in immunocompromised patients.•Amphotericin B is the primary therapy for severe disseminated histoplasmosis.•Long-term suppressive therapy with oral itraconazole may be required.
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ISSN:1201-9712
1878-3511
DOI:10.1016/j.ijid.2017.06.018