Proliferating cell nuclear antigen (PCNA), p53 and MDM2 expression in Hodgkins disease

Tumor cells in Hodgkins disease (HD) express cell proliferation markers that are evaluated according to the oncogenes involved or the expression of their proteins. Correlations between the protein expression grade and clinical data are now important for disease prognosis. This was a retrospective an...

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Bibliographic Details
Published in:	São Paulo medical journal Vol. 125; no. 2; pp. 77 - 84
Main Authors:	Pinheiro, Gevina Silva, Silva, Maria Regina Régis, Rodrigues, Celso Arrais, Kerbauy, José, de Oliveira, José Salvador Rodrigues
Format:	Journal Article
Language:	English
Published:	Brazil Associação Paulista de Medicina - APM 01-03-2007 Associação Paulista de Medicina
Subjects:	Adolescent Adult Aged Aged, 80 and over Child Epidemiologic Methods Female Hodgkin disease Hodgkin Disease - metabolism Hodgkin Disease - pathology Humans Immunohistochemistry Lymphocytes - pathology Male MEDICINE, GENERAL & INTERNAL Middle Aged p53 genes Prognosis Proliferating cell nuclear antigen Proliferating Cell Nuclear Antigen - analysis Proto-oncogene proteins c-mdm2 Proto-Oncogene Proteins c-mdm2 - analysis Reed-Sternberg Cells - chemistry Tumor Suppressor Protein p53 - analysis Immunohistochemistry Genes p53 Proto-oncogene proteins c-mdm2 Proteínas proto-oncogênicas c-mdm2 Doença de Hodgkin Proliferating cell nuclear antigen Imunohistoquímica Hodgkin disease Antígeno nuclear de célula em proliferação p53 genes
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