Selective ortho‐Functionalization of Adamantylarenes Enabled by Dispersion and an Air‐Stable Palladium(I) Dimer

Contrary to the general belief that Pd‐catalyzed cross‐coupling at sites of severe steric hindrance are disfavored, we herein show that the oxidative addition to C−Br ortho to an adamantyl group is as favored as the corresponding adamantyl‐free system due to attractive dispersion forces. This enable...

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Bibliographic Details
Published in:	Angewandte Chemie International Edition Vol. 59; no. 20; pp. 7721 - 7725
Main Authors:	Kalvet, Indrek, Deckers, Kristina, Funes‐Ardoiz, Ignacio, Magnin, Guillaume, Sperger, Theresa, Kremer, Marius, Schoenebeck, Franziska
Format:	Journal Article
Language:	English
Published:	Germany Wiley Subscription Services, Inc 11-05-2020 John Wiley and Sons Inc
Edition:	International ed. in English
Subjects:	Alkylation chemoselectivity Communication Communications Cross coupling DFT calculations Dimers Dispersion homogeneous catalysis Palladium Steric hindrance cross-coupling chemoselectivity palladium homogeneous catalysis DFT calculations
Online Access:	Get full text
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