Progressive Impairment of NK Cell Cytotoxic Degranulation Is Associated With TGF-β1 Deregulation and Disease Progression in Pancreatic Cancer

Natural killer (NK) cells are key effectors in cancer immunosurveillance and can be used as a prognostic biomarker in diverse cancers. Nonetheless, the role of NK cells in pancreatic cancer (PC) remains elusive, given conflicting data on their association with disease prognosis. In this study, using...

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Bibliographic Details

Published in:	Frontiers in immunology Vol. 10; p. 1354
Main Authors:	Jun, Eunsung, Song, Ah Young, Choi, Ji-Wan, Lee, Hyeon Ho, Kim, Mi-Yeon, Ko, Dae-Hyun, Kang, Hyo Jeong, Kim, Seong Who, Bryceson, Yenan, Kim, Song Cheol, Kim, Hun Sik
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 2019
Subjects:	cytotoxicity Immunology Medicin och hälsovetenskap natural killer cells pancreatic cancer prognosis TGF-β1 natural killer cells TGF-β1 pancreatic cancer prognosis cytotoxicity
Online Access:	Get full text
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