Cellulitis and Nodular Skin Lesions Due to Fusarium spp in Liver Transplant: Case Report

• Published in: Transplantation proceedings Vol. 42; no. 2; pp. 599 - 600
• Main Authors: Halpern, M, Balbi, E, Carius, L, Roma, J, Gonzalez, A.C, Agoglia, L, Covelo, M, Araujo, A, Guedes, C, Alves, J, Enne, M, Martinho, J.M, Pacheco, L
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01-03-2010; Elsevier
• Subjects: Amphotericin B - therapeutic use; Biological and medical sciences; Biopsy; Cellulitis - microbiology; Cellulitis - pathology; Dermatology; Fundamental and applied biological sciences. Psychology; Fundamental immunology; Fusarium; Graft Rejection - pathology; Hepatitis C - surgery; Humans; Liver Cirrhosis - surgery; Liver Transplantation - adverse effects; Male; Medical sciences; Middle Aged; Mycoses - drug therapy; Mycoses - pathology; Pyrimidines - therapeutic use; Skin - microbiology; Skin - pathology; Skin involvement in other diseases. Miscellaneous. General aspects; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tissue, organ and graft immunology; Treatment Outcome; Triazoles - therapeutic use; Voriconazole; Human; Skin disease; Digestive system; Liver; Transplantation; Cellulitis; Homotransplantation; Fungi; Case study; Medicine; Treatment; Surgery; Fusarium; Graft; Fungi Imperfecti; Adipose tissue disorders
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2010.01.004

Abstract Fusariosis is one of the emerging invasive fungal infections over the last decade. However, its recent rise has been in its ability to produce disseminated infection in severely immunosuppressed patients with neutropenia. In solid organ transplantation, fusariosis remains an uncommon picture mainly with nodules, subcutaneous abscesses, ulcers, or necrotic skin lesions resembling erthyma gangrenosum. Herein, we have reported a case of cellulitis, subcutaneous nodules, and abscesses due to Fusarium spp in a liver transplantation patient who was successfully treated with polyenes and surgical resection.