Clinical Experience of More Than 200 Cases of Pediatric Liver Transplantation at a Single Center: Improved Patient Survival

• Published in: Transplantation proceedings Vol. 44; no. 2; pp. 484 - 486
• Main Authors: Oh, S.H, Kim, K.M, Kim, D.Y, Song, S.M, Kim, T, Hwang, S, Park, K.-M, Lee, Y.-J, Lee, S.-G
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Amsterdam Elsevier Inc 01-03-2012; Elsevier
• Subjects: Age Factors; Biological and medical sciences; Chi-Square Distribution; Female; Fundamental and applied biological sciences. Psychology; Fundamental immunology; General aspects; Humans; Infant; Infant, Newborn; Kaplan-Meier Estimate; Liver Transplantation - adverse effects; Liver Transplantation - mortality; Liver, biliary tract, pancreas, portal circulation, spleen; Male; Medical sciences; Reoperation; Republic of Korea; Retrospective Studies; Risk Assessment; Risk Factors; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the digestive system; Survival Rate; Time Factors; Tissue, organ and graft immunology; Treatment Outcome; Republic of Korea; Human; Pediatrics; Center; Prognosis; Digestive system; Liver; Patient; Homotransplantation; Survival; Case study; Medicine; Experience; Treatment; Surgery; Graft; Child; Liver transplantation
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2012.02.002

Abstract The aim of this study was to present our experience with more than 200 cases of orthotopic liver transplantation (OLT) at a single center. We conducted a retrospective, single-center assessment of the demographic and clinical factors in children who underwent OLT from 1994 to 2010. Two hundred children younger than 18 years of age underwent 200 primary and 9 liver re-transplantations. The overall patient survival rates before 2003 at 1, 5, and 10 years were 86.4%, 79.5%, and 78.4%, respectively; whereas after 2003 they were 95.4% and 95.4% at 1 and 5 years, respectively ( P < .05). Our center's results showed durable, improved outcomes in recent years.