Visualization of early events in tumor formation of eGFP-transfected rat colon cancer cells in liver

Colon cancer preferentially metastasizes to the liver. To determine cellular backgrounds of this preference, we generated an enhanced green fluorescent protein (eGFP)-expressing rat adenocarcinoma cell line (CC531s) that forms metastases in rat liver after administration to the portal vein. Intravit...

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Bibliographic Details
Published in:	Hepatology (Baltimore, Md.) Vol. 38; no. 2; pp. 295 - 304
Main Authors:	Mook, Olaf R.F., Van Marle, Jan, Vreeling-Sindelárová, Heleen, Jonges, Remmet, Frederiks, Wilma M., Van Noorden, Cornelis J.F.
Format:	Journal Article
Language:	English
Published:	Philadelphia, PA Elsevier Inc 01-08-2003 W.B. Saunders Wiley
Subjects:	Animals Biological and medical sciences Carcinoma - secondary Colonic Neoplasms - pathology Gastroenterology. Liver. Pancreas. Abdomen Green Fluorescent Proteins In Vitro Techniques Indicators and Reagents - metabolism Liver Neoplasms - secondary Luminescent Proteins - genetics Male Medical sciences Microscopy, Electron Neoplasm Transplantation Portal Vein Rats Rats, Inbred Strains Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Transfection Tumor Cells, Cultured - transplantation Tumor Cells, Cultured - ultrastructure Tumors Visualization Carcinoma Rat Liver Rodentia Hepatic disease Tumoral marker Malignant tumor Enhancement factor Metastasis Electron microscopy Colonic disease Anatomic pathology Vertebrata Mammalia Cell line Animal Green fluorescent protein Digestive diseases Intestinal disease Early Colon
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