Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies

The coronavirus disease-19 (COVID-19) outbreak that is caused by a highly contagious severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a zoonotic pandemic, with approximately 24.5 million positive cases and 8.3 lakhs deaths globally. The lack of effective drugs or vaccine provo...

Full description

Saved in:

Bibliographic Details
Published in:	European journal of pharmacology Vol. 890; p. 173688
Main Authors:	M, Pooja, Reddy, Gangavaram Jyothi, Hema, Kanipakam, Dodoala, Sujatha, Koganti, Bharathi
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 05-01-2021
Subjects:	Antiviral Agents - pharmacology Benzamidines Berberine - analogs & derivatives Berberine - pharmacology Binding Sites COVID-19 COVID-19 Drug Treatment Diterpenes - pharmacology Drug repurposing Flavanones - pharmacology Flavonoids - pharmacology Full Length Guanidines - pharmacology Homology modelling Lactones - pharmacology Lanosterol - analogs & derivatives Lanosterol - pharmacology Meloxicam - pharmacology Models, Molecular Molecular docking Proanthocyanidins - pharmacology Protein Binding SARS-CoV-2 Serine Endopeptidases - metabolism Serine Proteinase Inhibitors - pharmacology TMPRSS2 COVID-19 Drug repurposing TMPRSS2 SARS-CoV-2 Homology modelling Molecular docking
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!