Generation of integration-free induced pluripotent stem cells (GZHMUi001-A) by reprogramming peripheral blood mononuclear cells from a 47, XXX syndrome patient

47, XXX syndrome is one of several sex-chromosomal aneuploidies, and it has an incidence of approximately 1/1000 in newborn females. Because of heterogeneity in X-inactivation, these patients may exhibit a variety of clinical symptoms. Here, we report the generation of an integration-free human indu...

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Bibliographic Details

Published in:	Stem cell research Vol. 23; no. C; pp. 57 - 60
Main Authors:	Chen, Yuchang, Ou, Zhanhui, Song, Bing, Xian, Yexing, Ouyang, Shuming, Xie, Yuhuan, Xue, Yanting, Sun, Xiaofang
Format:	Journal Article
Language:	English
Published:	England Elsevier B.V 01-08-2017 Elsevier
Subjects:	Cell Culture Techniques - methods Cellular Reprogramming Chromosomes, Human, X Female Humans Induced Pluripotent Stem Cells - pathology Leukocytes, Mononuclear - pathology Sex Chromosome Aberrations Sex Chromosome Disorders of Sex Development - pathology Trisomy - pathology Young Adult
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