Caspase-3 Inhibition Attenuates the Cytopathic Effects of EV71 Infection

Previous studies demonstrate that human enterovirus 71 (EV71), a primary causative agent for hand, foot, and mouth disease, activates caspase-3 through the non-structural viral 3C protein to induce host cell apoptosis; however, until now it was unclear how 3C activates caspase-3 and how caspase-3 ac...

Full description

Bibliographic Details

Published in:	Frontiers in microbiology Vol. 9; p. 817
Main Authors:	Song, Fengmei, Yu, Xiaoyan, Zhong, Ting, Wang, Zengyan, Meng, Xiangling, Li, Zhaolong, Zhang, Shuxia, Huo, Wenbo, Liu, Xin, Zhang, Yahong, Zhang, Wenyan, Yu, Jinghua
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 26-04-2018
Subjects:	caspase-3 EV71 host–pathogen interaction Microbiology non-structural protein 3C viral production EV71 non-structural protein 3C viral production host–pathogen interaction caspase-3
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!