The Role of CXCR3 and Associated Chemokines in the Development of Atherosclerosis and During Myocardial Infarction

The chemokine receptor CXCR3 and associated CXC chemokines have been extensively investigated in several inflammatory and autoimmune diseases as well as in tumor development. Recent studies have indicated the role of these chemokines also in cardiovascular diseases. We aimed to present current knowl...

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Published in:Frontiers in immunology Vol. 9; p. 1932
Main Authors: Szentes, Veronika, Gazdag, Mária, Szokodi, István, Dézsi, Csaba A
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 27-08-2018
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Summary:The chemokine receptor CXCR3 and associated CXC chemokines have been extensively investigated in several inflammatory and autoimmune diseases as well as in tumor development. Recent studies have indicated the role of these chemokines also in cardiovascular diseases. We aimed to present current knowledge regarding the role of CXCR3-binding chemokines in the pathogenesis of atherosclerosis and during acute myocardial infarction.
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This article was submitted to Cytokines and Soluble Mediators in Immunity, a section of the journal Frontiers in Immunology
Edited by: Pietro Enea Lazzerini, University of Siena, Italy
These authors have contributed equally to this work
Reviewed by: Jose Miguel Rodriguez Frade, Consejo Superior de Investigaciones Científicas (CSIC), Spain; Raffaele Altara, Oslo University Hospital, Norway
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2018.01932