Investigation of standing balance in diabetic patients with and without peripheral neuropathy using accelerometers

• Published in: Clinical biomechanics (Bristol) Vol. 24; no. 9; pp. 716 - 721
• Main Authors: Turcot, K, Allet, L, Golay, A, Hoffmeyer, P, Armand, S
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01-11-2009
• Subjects: Acceleration; Accelerometry; Diabetes; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - physiopathology; Diabetic Nephropathies - diagnosis; Diabetic Nephropathies - physiopathology; Female; Humans; Male; Middle Aged; Monitoring, Ambulatory - methods; Peripheral neuropathy; Physical Medicine and Rehabilitation; Postural Balance; Postural stability; Posture; Standing balance; Diabetes; Peripheral neuropathy; Standing balance; Postural stability; Accelerometry
• ISSN: 0268-0033; 1879-1271
• DOI: 10.1016/j.clinbiomech.2009.07.003

Abstract Background Peripheral neuropathy is recognised to be the most symptomatic complication of diabetes and is also linked to postural instability. This study investigates balance instability in diabetic patients with and without peripheral neuropathy. Methods Quiet standing balance was investigated using an accelerometric-based method in 24 diabetic patients (12 with and 12 without peripheral neuropathy) and compared with 12 control subjects. Accelerations were measured at lumbar and ankle levels using three accelerometers. Two standing conditions of 30 s were evaluated (i.e., eyes opened, eyes closed). The range and root mean square values were calculated on the anterior posterior component of lumbar and ankle accelerations and for the medial lateral component of lumbar accelerations. Differences between parameters were compared between groups using ANOVA and post hoc comparisons. Findings The diabetic patients with peripheral neuropathy show higher-range and root mean square values compared with those of control subjects and diabetic patients without peripheral neuropathy. Significant differences between groups have been detected for anterior posterior range of lumbar acceleration, which was significantly higher for diabetic patients with peripheral neuropathy, compared with those of others groups. Significant higher values for diabetic patients with peripheral neuropathy were also detected for anterior posterior range and root mean square of ankle accelerations compared with control subjects. Visual deprivation shows an increase in accelerometric parameters for each group. Interpretation This study is the first to investigate the balance instability of diabetic patients using accelerometers. Results confirm that diabetic patients with peripheral neuropathy have greater postural instability with higher acceleration values than those of control group and diabetic patients without peripheral neuropathy.