Comparing palliative treatment options for cholangiocarcinoma: photodynamic therapy vs. radiofrequency ablation

Referral to an endoscopist is often done once curative resection is no longer an option for cholangiocarcinoma management. In such cases, palliation has become the main objective of the treatment. Photodynamic therapy and radiofrequency ablation can be performed to achieve palliation, with both proc...

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Bibliographic Details
Published in:Clinical endoscopy Vol. 55; no. 3; pp. 347 - 354
Main Authors: Mohammad, Tayyaba, Kahaleh, Michel
Format: Journal Article
Language:English
Published: Korea (South) Korean Society of Gastrointestinal Endoscopy 01-05-2022
대한소화기내시경학회
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Summary:Referral to an endoscopist is often done once curative resection is no longer an option for cholangiocarcinoma management. In such cases, palliation has become the main objective of the treatment. Photodynamic therapy and radiofrequency ablation can be performed to achieve palliation, with both procedures associated with improved stent patency and survival. Despite the greatly increased cost and association with photosensitivity, photodynamic therapy allows transmission to the entire biliary tree. In contrast, radiofrequency ablation is cheaper and faster to apply but requires intraductal contact. This paper reviews both modalities and compares their efficacy and safety for bile duct cancer palliation.
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https://doi.org/10.5946/ce.2021.274
ISSN:2234-2400
2234-2443
DOI:10.5946/ce.2021.274