A new antimicrobial quinolone (AM-1155) analysed in hair as an index of drug exposure and as a time-marker

Scalp hair samples were obtained at one-month intervals for up to four months after the administration from each of twelve healthy male volunteers participating in a phase I study of a new antimicrobial quinolone, AM-1155, (+/-)-1-cyclopropyl-6-fluoro-1, 4-dihydro-8-methoxy-7-(cis-3,5-dimethyl-1-pip...

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Bibliographic Details

Published in:	Journal of pharmacy and pharmacology Vol. 45; no. 11; p. 1012
Main Authors:	Uematsu, T, Kusajima, H, Umemura, K, Ishida, R, Ohkubo, H, Nakashima, M
Format:	Journal Article
Language:	English
Published:	England 01-11-1993
Subjects:	Adult Anti-Infective Agents - analysis Biomarkers Chromatography, High Pressure Liquid Fluoroquinolones Gatifloxacin Hair - chemistry Hair - growth & development Humans Male Piperazines - analysis Quinolones - analysis Spectrometry, Fluorescence
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