Endothelium-derived 2-arachidonylglycerol: an intermediate in vasodilatory eicosanoid release in bovine coronary arteries

Acetylcholine stimulates the release of endothelium-derived arachidonic acid (AA) metabolites including prostacyclin and epoxyeicosatrienoic acids (EETs), which relax coronary arteries. However, mechanisms of endothelial cell (EC) AA activation remain undefined. We propose that 2-arachidonylglycerol...

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Bibliographic Details
Published in:	American journal of physiology. Heart and circulatory physiology Vol. 288; no. 3; p. H1344
Main Authors:	Gauthier, Kathryn M, Baewer, David V, Hittner, Sarah, Hillard, Cecilia J, Nithipatikom, Kasem, Reddy, D Sudarshan, Falck, J R, Campbell, William B
Format:	Journal Article
Language:	English
Published:	United States 01-03-2005
Subjects:	8,11,14-Eicosatrienoic Acid - analogs & derivatives 8,11,14-Eicosatrienoic Acid - metabolism Animals Arachidonic Acid - pharmacokinetics Arachidonic Acids - metabolism Carbon Radioisotopes Cattle Cells, Cultured Coronary Vessels - cytology Coronary Vessels - physiology Endocannabinoids Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Glycerides - metabolism Hydroxyeicosatetraenoic Acids - metabolism Vasodilation - physiology
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