Effect of short-term therapy with ceftizoxime and ceftriaxone on human peripheral WBC, serum immunoglobulins and lymphocyte subpopulations

Effect of short-term therapy with ceftizoxime and ceftriaxone on human peripheral WBC, serum immunoglobulins and lymphocyte subpopulations

Serum immunoglobulins, peripheral white blood cells and lymphocyte subpopulation counts of twenty patients who received ceftizoxime and ceftriaxone for antimicrobial prophilaxis in surgery were examined in order to obtain a profile of the effects of these drugs on humoral and cellular immune system...

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Bibliographic Details
Published in:Immunopharmacology and immunotoxicology Vol. 17; no. 4; p. 775
Main Authors: Karakaya, A, Gümüşay, S, Yücesoy, B, Hengirmen, S
Format: Journal Article
Language:English
Published: England 01-01-1995
Subjects:
Adult
Ceftizoxime - pharmacology
Ceftriaxone - pharmacology
Cephalosporins - pharmacology
Female
Humans
Immunoglobulins - blood
Leukocytes - drug effects
Lymphocyte Subsets - drug effects
Male
Middle Aged
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Summary:Serum immunoglobulins, peripheral white blood cells and lymphocyte subpopulation counts of twenty patients who received ceftizoxime and ceftriaxone for antimicrobial prophilaxis in surgery were examined in order to obtain a profile of the effects of these drugs on humoral and cellular immune system of human. No differences in the serum concentrations of IgG, IgM, IgA, peripheral blood lymphocytes and lymphocyte subpopulations 24 h and 48 h following the last dose of these two drugs were observed.
ISSN:0892-3973
DOI:10.3109/08923979509037195