Genistein modulates immune responses and increases host resistance to B16F10 tumor in adult female B6C3F1 mice

The isoflavone genistein (4,7,4'-trihydroxyisoflavone) is a phytoestrogen found in high levels in soy products that has been associated with decreased incidences of breast and prostate cancers. The potential effects of genistein on the immune system were evaluated in adult female B6C3F1 mice. G...

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Bibliographic Details
Published in:	The Journal of nutrition Vol. 131; no. 12; p. 3251
Main Authors:	Guo, T L, McCay, J A, Zhang, L X, Brown, R D, You, L, Karrow, N A, Germolec, D R, White, Jr, K L
Format:	Journal Article
Language:	English
Published:	United States 01-12-2001
Subjects:	Animals Anticarcinogenic Agents - pharmacology CD8-Positive T-Lymphocytes - immunology Cell Division Female Genistein - pharmacology Immunity - drug effects Immunity, Innate - drug effects Interferon-gamma - pharmacology Lipopolysaccharides - pharmacology Lung Neoplasms - pathology Lung Neoplasms - prevention & control Lymphocyte Culture Test, Mixed Macrophages, Peritoneal - immunology Melanoma, Experimental - immunology Melanoma, Experimental - pathology Melanoma, Experimental - prevention & control Mice Neoplasm Transplantation T-Lymphocytes, Cytotoxic - immunology Tumor Cells, Cultured
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