Chromosomal Assignment of a Family of Human Oncogenes

A family of human transforming genes, previously shown to share homology with the ras family of viral oncogenes, maps to three different human chromosomes. A wellcharacterized mouse-human hybrid cell panel, combined with Southern blotting, was used in this study. The transforming gene of the T24 bla...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 80; no. 14; pp. 4460 - 4463
Main Authors:	Ryan, James, Barker, P. E., Shimizu, Kenji, Wigler, Michael, Ruddle, Frank H.
Format:	Journal Article
Language:	English
Published:	United States National Academy of Sciences of the United States of America 01-07-1983 National Acad Sciences
Subjects:	Animals Cell Line Cell lines Cell Transformation, Neoplastic Chromosomes Chromosomes, Human - physiology Genes Genes, Viral Genetic mapping Human chromosomes Humans Hybrid Cells Hybridity Lung Neoplasms - genetics Mice Neuroblastoma - genetics Nucleic Acid Hybridization Oncogenes Retroviridae - genetics Transformed cell line Tumor cell line
Online Access:	Get full text
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