Mechanisms of renal NaCl retention in proteinuric disease

In diseases with proteinuria, for example nephrotic syndrome and pre‐eclampsia, there often are suppression of plasma renin–angiotensin–aldosterone system components, expansion of extracellular volume and avid renal sodium retention. Mechanisms of sodium retention in proteinuria are reviewed. In ani...

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Bibliographic Details
Published in:	Acta Physiologica Vol. 207; no. 3; pp. 536 - 545
Main Authors:	Svenningsen, P., Friis, U. G., Versland, J. B., Buhl, K. B., Møller Frederiksen, B., Andersen, H., Zachar, R. M., Bistrup, C., Skøtt, O., Jørgensen, J. S., Andersen, R. F., Jensen, B. L.
Format:	Journal Article
Language:	English
Published:	England Blackwell Publishing Ltd 01-03-2013 Wiley Subscription Services, Inc
Subjects:	Animals Blood Pressure Disease Models, Animal Diuretics - therapeutic use ENaC Epithelial Sodium Channels - drug effects Epithelial Sodium Channels - metabolism Fibrinolysin - metabolism Glomerular Filtration Rate Humans hypertension Ion Channel Gating Kidney - drug effects Kidney - metabolism Kidney - physiopathology Kidney Diseases - drug therapy Kidney Diseases - metabolism Kidney Diseases - physiopathology Kidney Diseases - urine Kidneys nephrosis oedema plasmin pre-eclampsia Preeclampsia Proteins proteinuria Proteinuria - drug therapy Proteinuria - metabolism Proteinuria - physiopathology Proteinuria - urine Renin-Angiotensin System Retention Rodents Sodium Sodium Chloride, Dietary - metabolism Sodium Chloride, Dietary - urine Water-Electrolyte Balance
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