Familial Arteriovenous Malformations of the Brain —Two Case Reports

• Published in: Neurologia medico-chirurgica Vol. 34; no. 4; pp. 221 - 224
• Main Authors: GOTO, Shin, ABE, Masamitsu, TSUJI, Takehisa, TABUCHI, Kazuo
• Format: Journal Article
• Language: English
• Published: Japan The Japan Neurosurgical Society 1994
• Subjects: Adult; arteriovenous malformation; brain; Cerebral Angiography; Cerebral Hemorrhage - diagnostic imaging; Cerebral Hemorrhage - genetics; familial arteriovenous malformation; Female; Frontal Lobe - blood supply; Humans; Intracranial Arteriovenous Malformations - diagnostic imaging; Intracranial Arteriovenous Malformations - genetics; Parietal Lobe - blood supply; Rupture, Spontaneous
• ISSN: 0470-8105; 1349-8029
• DOI: 10.2176/nmc.34.221

Familial arteriovenous malformation (AVM) of the brain is an uncommon entity. A 24-year-old female presented with sudden onset of left hemiparesis due to an AVM with a hematoma in the right frontal lobe, which was surgically removed. Her 23-year-old younger sister presented with motor aphasia and right hemiparesis due to an AVM with a hematoma in the left frontoparietal lobes, which was surgically removed. Thirty-two patients in 15 families have been described in total. The mean age of these patients was 28 years, with 15 males and 17 females. Multiple AVMs occurred in four patients (12.5%), more frequently than in non-familial cases.