Prevalence of Candida bloodstream isolates from patients in two hospitals in Vietnam

• Published in: Iranian journal of microbiology Vol. 11; no. 2; pp. 108 - 113
• Main Authors: Bac, Nguyen Duy, Anh, Le Tran, Quang, Le Bach, Luc, Nguyen Khac, Nga, Tran Thi Thanh, Nagi, Minoru, Yoshitsugu, Miyazaki, Ha, Hoang Thi Thu, Anh, Dang Duc, Quyet, Do, Anh, Do Ngoc
• Format: Journal Article
• Language: English
• Published: Iran Tehran University of Medical Sciences 01-04-2019
• Subjects: Original; Prevalence; Candida; Bloodstream; Vietnam; Vietnam; Prevalence; Candida; Bloodstream
• ISSN: 2008-3289; 2008-4447
• DOI: 10.18502/ijm.v11i2.1071

Identification of yeasts provides helpful information for appropriate administration of anti-fungal treatments; however, few reports from the Vietnam have been published. This study has been performed to find the prevalence of
blood stream isolates from patients in two hospitals in Vietnam.
spp. were isolated from blood cultures in two hospitals, Vietnam between May 2013 and May 2015. Participating hospitals were 103 Military Hospital, Ha Noi city (550 beds) and Cho Ray Hospital, Ho Chi Minh city (1800 beds). All the bloodstream isolates were identified to species level by the germ tube test and polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). In addition, unknown isolates were subjected to PCR sequencing.
A total of 93
isolates were isolated from blood cultures during the study period. The results of this study showed that
(n = 47, 50.54%) was the most common agent, followed by
(n = 18, 19.35%),
(n = 16, 17.20%),
(n = 6, 6.45%),
(n = 5, 5.38%) and
(n = 1, 1.08%), respectively.
The frequency of the non-
species in blood is increasing, especially
. Additional investigations should be made to clarify the epidemiological profile of invasive
bloodstream in Vietnam.