Postoperative subcutaneous instillation of low-dose ketorolac but not hydromorphone reduces wound exudate concentrations of interleukin-6 and interleukin-10 and improves analgesia following cesarean delivery

The objectives of this study were to test the effects of low-dose ketorolac and hydromorphone added to continuous local anesthetic wound instillation on surgical-site inflammatory mediators, postoperative pain, and opioid consumption. Sixty healthy women undergoing cesarean delivery were enrolled in...

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Bibliographic Details
Published in:	The journal of pain Vol. 14; no. 1; p. 48
Main Authors:	Carvalho, Brendan, Lemmens, Harry J, Ting, Vicki, Angst, Martin S
Format:	Journal Article
Language:	English
Published:	United States 01-01-2013
Subjects:	Adult Analgesics, Opioid - administration & dosage Analgesics, Opioid - therapeutic use Anesthetics, Local - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - administration & dosage Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Bupivacaine - therapeutic use Cesarean Section Cytokines - metabolism Double-Blind Method Exudates and Transudates - metabolism Female Humans Hydromorphone - administration & dosage Hydromorphone - therapeutic use Injections, Subcutaneous Interleukin-10 - metabolism Interleukin-6 - metabolism Ketorolac - administration & dosage Ketorolac - therapeutic use Pain Measurement - drug effects Pain, Postoperative - prevention & control Postoperative Care Pregnancy
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