Neurobiology of the nicotine withdrawal syndrome

The aversive aspects of withdrawal from chronic nicotine exposure are thought to be an important motivational factor contributing to the maintenance of the tobacco habit in human smokers. Much emphasis has been placed on delineating the underlying neurobiological mechanisms mediating different compo...

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Bibliographic Details
Published in:	Pharmacology, biochemistry and behavior Vol. 70; no. 4; pp. 531 - 549
Main Authors:	Kenny, Paul J., Markou, Athina
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-12-2001
Subjects:	Acetylcholine Animals Conditioned place aversion Depression Dopamine Drug withdrawal Glutamate Humans Intracranial self-stimulation Nicotine Nicotine - adverse effects Nicotinic Agonists - adverse effects Opioid Reward Serotonin Somatic signs Substance Withdrawal Syndrome - metabolism Dopamine Serotonin Conditioned place aversion Opioid Drug withdrawal Somatic signs Depression Intracranial self-stimulation Acetylcholine Reward Glutamate Nicotine
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